Structure of PDB 3w2w Chain A

Receptor sequence
>3w2wA (length=618) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
VKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFG
PEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIE
EEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREY
FTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIA
IYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHD
NLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWR
KIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGDEEKVKEV
VDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLYSTPQVHVAISQA
LANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKS
FELLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGL
LKRSGSYYISLVGWELIRVFYNSELRKKLLEEGVGKRFIYHVLREVDTWP
KVGIDEMLKFEVIRHIRGRNKEETKELREKIYGEIKDLLEHVRGNNEVEK
VRGLFTFLKIITDAEVFP
3D structure
PDB3w2w Crystal Structure of the Cmr2-Cmr3 Subcomplex in the CRISPR-Cas RNA Silencing Effector Complex.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F264 I270
Catalytic site (residue number reindexed from 1) F49 I55
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C448 C451 C478 C481 C233 C236 C263 C266
BS02 ATP A V229 Q230 I233 S246 N300 R436 Y669 D674 V14 Q15 I18 S31 N85 R221 Y421 D426
BS03 ATP A Y271 K301 D600 G601 D603 M604 G605 I608 H642 K739 K744 Y56 K86 D374 G375 D377 M378 G379 I382 H394 K488 K493
BS04 MG A D600 G601 D374 G375
External links
PDB RCSB:3w2w, PDBe:3w2w, PDBj:3w2w
PDBsum3w2w
PubMed23583914
UniProtQ8U1S6|CMR2_PYRFU CRISPR system Cmr subunit Cmr2 (Gene Name=cmr2)

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