Structure of PDB 3w0j Chain A

Receptor sequence
>3w0jA (length=242) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLAD
LVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMD
DMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVL
LMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAK
MIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
3D structure
PDB3w0j Structural basis for vitamin D receptor agonism by novel non-secosteroidal ligands.
ChainA
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 S252 Q255 I256 K260 P412 E416 I60 K64 S74 Q77 I78 K82 P234 E238
BS02 T08 A L223 A227 L229 V230 S233 I267 R270 S271 W282 H301 H393 L45 A49 L51 V52 S55 I89 R92 S93 W104 H123 H215
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3w0j, PDBe:3w0j, PDBj:3w0j
PDBsum3w0j
PubMed23462137
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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