Structure of PDB 3vxx Chain A

Receptor sequence
>3vxxA (length=63) Species: 10090 (Mus musculus) [Search protein sequence]
PVPCGWERVVKQRLSGKTAGKFDVYFISPQGLKFRSKRSLANYLLKNGET
FLKPEDFNFTVLP
3D structure
PDB3vxx Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
ChainA
Resolution2.204 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R106 S107 K108 R109 R35 S36 K37 R38 PDBbind-CN: Kd=97.5nM
BS02 dna A K82 R84 L85 S86 G87 K88 T89 K11 R13 L14 S15 G16 K17 T18 PDBbind-CN: Kd=97.5nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3vxx, PDBe:3vxx, PDBj:3vxx
PDBsum3vxx
PubMed23316048
UniProtQ9Z2D7|MBD4_MOUSE Methyl-CpG-binding domain protein 4 (Gene Name=Mbd4)

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