Structure of PDB 3vxv Chain A

Receptor sequence
>3vxvA (length=65) Species: 10090 (Mus musculus) [Search protein sequence]
KPVPCGWERVVKQRLSGKTAGKFDVYFISPQGLKFRSKRSLANYLLKNGE
TFLKPEDFNFTVLPK
3D structure
PDB3vxv Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R106 S107 K108 R109 R36 S37 K38 R39 PDBbind-CN: Kd=98.8nM
BS02 dna A K82 R84 L85 S86 G87 K88 T89 K12 R14 L15 S16 G17 K18 T19 PDBbind-CN: Kd=98.8nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3vxv, PDBe:3vxv, PDBj:3vxv
PDBsum3vxv
PubMed23316048
UniProtQ9Z2D7|MBD4_MOUSE Methyl-CpG-binding domain protein 4 (Gene Name=Mbd4)

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