Structure of PDB 3vxj Chain A

Receptor sequence

>3vxjA (length=438) Species: 5331 (Bjerkandera adusta)

ILPLNNIQGDILVGMKKQKERFVFFQVNDATSFKTALKTYVPERITSAAI
LISDPSQQPLAFVNLGFSNTGLQALGITDDLGDAQFPDGQFADAANLGDD
LSQWVAPFTGTTIHGVFLIGSDQDDFLDQFTDDISSTFGSSITQVQALSG
SARPGDQAGHEHFGFLDGISQPSVTGWETTVFPGQAVVPPGIILTGRDGD
TGTRPSWALDGSFMAFRHFQQKVPEFNAYTLANAIPANSAGNLTQQEGAE
FLGARMFGRWKSGAPIDLAPTADDPALGADPQRNNNFDYSDTLTDETRCP
FGAHVRKTNPRQDLGGPVDTFHAMRSSIPYGPETSDAELASGVTAQDRGL
LFVEYQSIIGNGFRFQQINWANNANFPFSKPITPGIEPIIGQTTPRTVGG
LDPLNQNETFTVPLFVIPKGGEYFFLPSISALTATIAA

3D structure

• PDB: 3vxj Dye-decolorizing peroxidase (DyP) complex with 2,6-dimethoxyphenol
• Chain: A
• Resolution: 1.39 Å

Enzymatic activity

• Enzyme Commision number: 1.11.1.19: dye decolorizing peroxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	E165 L170 D171 G172 I173 S174 F223 Q225 F261 H308 V309 T312 N313 R315 R329 L354 F356 F367 Q370 I394 V420	E161 L166 D167 G168 I169 S170 F219 Q221 F257 H304 V305 T308 N309 R311 R325 L350 F352 F363 Q366 I390 V416
BS02	3DM	A	G188 N313 R315 H326	G184 N309 R311 H322
BS03	3DM	A	T298 S383 K384 P385	T294 S379 K380 P381

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:3vxj, PDBe:3vxj, PDBj:3vxj
• PDBsum: 3vxj
• UniProt: Q8WZK8