Structure of PDB 3vvp Chain A

Receptor sequence
>3vvpA (length=420) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
KTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGIWVSGLGPESL
AAVGLFFPVFMGIIALAAGLGVGTSSAIARRIGARDKEGADNVAVHSLIL
SLILGVTITITMLPAIDSLFRAVELAIEYARVLLAGAFIIVFNNVGNGIL
RGEGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATLLSMVVTS
LFIAYWLFVKRDTYVDIDFSPSREILKDILRVGLPSSLSQLSMSIAMFFL
NSVAITAGGENGVAVFTSAWRITMLGIVPILGMAAATTSVTGAAYGERNV
EKLETAYLYAIKIAFMIELAVVAFIMLDLISALRTLPVFLVLTPFGMMTS
AMFQGIGEGEKSLILTIFRTLVMQVGFAYIFVHYTTLGLRGVWIGIVIGN
MVAAIVGFLWGRMRISALKK
3D structure
PDB3vvp Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.
ChainA
Resolution2.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BNU A Q34 Y37 N153 N157 A172 M173 G176 N180 T202 S205 M206 T209 I213 Q31 Y34 N143 N147 A162 M163 G166 N170 T192 S195 M196 T199 I203
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0042910 xenobiotic transmembrane transporter activity
Biological Process
GO:0042908 xenobiotic transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vvp, PDBe:3vvp, PDBj:3vvp
PDBsum3vvp
PubMed23535598
UniProtQ8U2X0

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