Structure of PDB 3vva Chain A

Receptor sequence
>3vvaA (length=266) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
TPVWGHTQLNRLSFLETVPVVPLRVSDESSEDRPTWSLPDIENVAITHKK
PNGLVDTLAYRSVRTCRWLFDTFSLYRFGSITESKVISRCLFLETVAGVP
GMVGGMLRHLSSLRYMTRDKGWINTLLVEAENERMHLMTFIELRQPGLPL
RVSIIITQAIMYLFLLVAYVISPRFVHRFVGYLEEEAVITYTGVMRAIDE
GRLRPTKNDVPEVARVYWNLSKNATFRDLINVIRADEAEHRVVNHTFADM
HEKRLQNSVNPFVVLK
3D structure
PDB3vva Structure of the trypanosome cyanide-insensitive alternative oxidase
ChainA
Resolution2.59 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A E123 E162 H165 E266 E94 E133 H136 E237
BS02 FE A E162 E213 E266 E133 E184 E237
BS03 CHW A C95 R96 F99 R118 F121 L122 L212 E215 A216 T219 C66 R67 F70 R89 F92 L93 L183 E186 A187 T190 PDBbind-CN: -logKd/Ki=9.32,IC50=0.48nM
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0009916 alternative oxidase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0010230 alternative respiration
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3vva, PDBe:3vva, PDBj:3vva
PDBsum3vva
PubMed23487766
UniProtQ26710|AOX_TRYBB Alternative oxidase, mitochondrial (Gene Name=AOX)

[Back to BioLiP]