Structure of PDB 3vt9 Chain A

Receptor sequence
>3vt9A (length=233) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDSQ
DYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSP
DRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLR
SLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
3D structure
PDB3vt9 Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 I256 L259 K260 P412 E416 I58 K62 I76 L79 K80 P225 E229
BS02 YI4 A Y143 Y147 F150 S233 R270 S271 S274 V296 H301 H393 Y21 Y25 F28 S53 R90 S91 S94 V109 H114 H206
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3vt9, PDBe:3vt9, PDBj:3vt9
PDBsum3vt9
PubMed23944708
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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