Structure of PDB 3vri Chain A

Receptor sequence
>3vriA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPW
IEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGC
DVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAR
VAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB3vri Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 Y59 E63 T73 E76 N77 I80 Y84 Y99 T143 W147 Y159 W167 Y171 Y6 Y8 Y58 E62 T72 E75 N76 I79 Y83 Y98 T142 W146 Y158 W166 Y170
BS02 1KX A Y9 Y74 V97 D114 S116 Y123 I124 W147 Y8 Y73 V96 D113 S115 Y122 I123 W146
External links
PDB RCSB:3vri, PDBe:3vri, PDBj:3vri
PDBsum3vri
PubMed22722860
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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