Structure of PDB 3vrh Chain A

Receptor sequence
>3vrhA (length=298) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
MKCKFCSREAYIKIHYPKMYLCEEHFKEYFERKVSRTIERYKLLTKDERI
LVAVSGGKDSAVTAYVLKKLGYNIECLHINLGISGYSEKSEEYAKKQCKL
IGAPLHIVRIKEILGYGIGEVKTRRPPCSYCGLTKRYIMNKFAYDNGFDA
IATGHNLDDEASFLLNNILHWNTEYLAKGGPILPQQGKFIKKVKPLYEVT
EREVVAYALAVGLEYIVEECPYTTLDMKGVLNELEEKRPGTKFNFVRGYL
KKKKLFEPKECKICRMPSSGDICAFCKFWGLKKEINFKVSSTDEEPFG
3D structure
PDB3vrh Crystallographic and mutational studies on the tRNA thiouridine synthetase TtuA.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C3 C22 H25 C3 C22 H25
BS02 ZN A C272 C275 C284 C287 C261 C264 C273 C276
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0002143 tRNA wobble position uridine thiolation
GO:0008033 tRNA processing
GO:0034227 tRNA thio-modification
Cellular Component
GO:0002144 cytosolic tRNA wobble base thiouridylase complex

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Cellular Component
External links
PDB RCSB:3vrh, PDBe:3vrh, PDBj:3vrh
PDBsum3vrh
PubMed23444054
UniProtO58038|TTUA_PYRHO tRNA-5-methyluridine(54) 2-sulfurtransferase (Gene Name=ttuA)

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