Structure of PDB 3vqe Chain A

Receptor sequence
>3vqeA (length=136) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAG
RWPVKTVHTDNGSNFTGATVRAACDWAGIKQESMNKELKKIIGQVRDQAE
HLKTAVQMAVFIHNHKRKGGYSAGERIVDIIATDIQ
3D structure
PDB3vqe Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FMQ A H185 R187 S195 G197 E198 H115 R117 S122 G124 E125
BS02 FMQ A P109 K111 P53 K55
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:3vqe, PDBe:3vqe, PDBj:3vqe
PDBsum3vqe
PubMed23139382
UniProtQ72498

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