Structure of PDB 3vqa Chain A

Receptor sequence
>3vqaA (length=141) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTSTTVKAACDWAGIKQEDGIPMNKELKKIIGQVR
DQAEHLKTAVQMAVFIHNHKRKGGIGGYSAGERIVDIIATD
3D structure
PDB3vqa Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLC A E87 K173 E32 K107
BS02 FRU A E87 E96 K103 E32 E41 K48
BS03 MWP A R107 W108 P109 I204 R52 W53 P54 I138
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3vqa, PDBe:3vqa, PDBj:3vqa
PDBsum3vqa
PubMed23139382
UniProtQ72498

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