Structure of PDB 3vq7 Chain A

Receptor sequence
>3vq7A (length=145) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAG
RWPVKTVHTDNGSNFTSTTVKAACDWAGIKQEDGIPYVIESMNKELKKII
GQVRDQAEHLKTAVQMAVFIHNHKRKGGIGGYSAGERIVDIIATD
3D structure
PDB3vq7 Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A E96 Y99 E40 Y43
BS02 FRU A V88 K173 V32 K111
BS03 SNU A R107 W108 P109 I204 R51 W52 P53 I142
BS04 SNU A A98 Y99 T125 A128 A129 W132 A42 Y43 T69 A72 A73 W76
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:3vq7, PDBe:3vq7, PDBj:3vq7
PDBsum3vq7
PubMed23139382
UniProtQ72498

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