Structure of PDB 3vq4 Chain A

Receptor sequence
>3vq4A (length=144) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
SSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTSTTVKAACDWAGIKQEDGIPIESMNKELKKIIG
QVRDQAEHLKTAVQMAVFIHNHKRKGGIGGYSAGERIVDIIATD
3D structure
PDB3vq4 Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0NX A R107 W108 P109 I204 A205 T206 R52 W53 P54 I141 A142 T143
BS02 0NX A Q95 Y99 T125 A128 W132 Q40 Y44 T70 A73 W77
BS03 0NX A Y83 G197 E198 Y28 G134 E135
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:3vq4, PDBe:3vq4, PDBj:3vq4
PDBsum3vq4
PubMed23139382
UniProtQ72498

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