Structure of PDB 3vps Chain A

Receptor sequence

>3vpsA (length=303) Species: 1079985 (Streptomyces chartreusis NRRL 3882) [Search protein sequence]

KHRILITGGAGFIGGHLARALVASGEEVTVLDDLRVPPMIPPEGTGKFLE
KPVLELEERDLSDVRLVYHLASHKSVPRSFKQPLDYLDNVDSGRHLLALC
TSVGVPKVVVGSTCEVYGQADTLPTPEDSPLSPRSPYAASKVGLEMVAGA
HQRASVAPEVGIVRFFNVYGPGERPDALVPRLCANLLTRNELPVEGDGEQ
RRDFTYITDVVDKLVALANRPLPSVVNFGSGQSLSVNDVIRILQATSPAA
EVARKQPRPNEITEFRADTALQTRQIGERSGGIGIEEGIRLTLEWWQSRD
LDD

3D structure

PDB

3vps Biosynthesis of nucleoside antibiotic tunicamycin proceeds via unique exo-glycal intermediates

Chain

Resolution

1.9 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	T119 C120 E121 Y143 K147 D182
Catalytic site (residue number reindexed from 1)	T113 C114 E115 Y137 K141 D176
Enzyme Commision number	4.2.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	UD1	A	K80 T119 C120 E121 Y143 N173 D182 A183 L184 R187 P199 V200 E201 Q206 R208 V242 R264 E267	K74 T113 C114 E115 Y137 N167 D176 A177 L178 R181 P193 V194 E195 Q200 R202 V236 R258 E261
BS02	NAD	A	G14 G17 F18 I19 D38 D39 R41 V42 P58 V59 L76 A77 S78 K80 T119 K147 F171 V174	G8 G11 F12 I13 D32 D33 R35 V36 P52 V53 L70 A71 S72 K74 T113 K141 F165 V168

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding

View graph for
Molecular Function

External links

PDB	RCSB:3vps, PDBe:3vps, PDBj:3vps
PDBsum	3vps
PubMed
UniProt	E5KJ94

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