Structure of PDB 3vmr Chain A

Receptor sequence
>3vmrA (length=227) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
RILLKILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPE
YVKGAFISMEDERFYNHHGFDLKGTTRALFSTISDRDGGSTITQQVVKNY
FYDNDRSFTRKVKELFVAHRVEKQYNKNEILSFYLNNIYFGDNQYTLEGA
ANHYFGTTVNKNSTTMSHITVLQSAILASKVNAPSVYNINNMSENFTQRV
STNLEKMKQQNYINETQYQQAMSQLNR
3D structure
PDB3vmr Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
ChainA
Resolution3.688 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.99.28: peptidoglycan glycosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M0E A Q137 K140 N141 R148 Y181 V223 N224 P226 S227 Q95 K98 N99 R106 Y139 V181 N182 P184 S185
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0008955 peptidoglycan glycosyltransferase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3vmr, PDBe:3vmr, PDBj:3vmr
PDBsum3vmr
PubMed22493270
UniProtQ99T05|MGT_STAAM Monofunctional glycosyltransferase (Gene Name=mgt)

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