Structure of PDB 3vll Chain A

Receptor sequence
>3vllA (length=703) Species: 272569 (Haloarcula marismortui ATCC 43049) [Search protein sequence]
KRPKSNQDWWPSKLNLEILDQNARDVGPVEDDFDYAEEFQKLDLEAVKSD
LEELMTSSQDWWPADYGHYGPLFIRMAWHSAGTYRTADGRGGAAGGRQRF
APINSWPDNANLDKARRLLLPIKQKYGQKISWADLMILAGNVAIESMGFK
TFGYAGGREDAFEEDKAVNWGPEDEFETQERFDEPGEIQEGLGASVMGLI
YVNPEGPDGNPDPEASAKNIRQTFDRMAMNDKETAALIAGGHTFGKVHGA
DDPEENLGPEPEAAPIEQQGLGWQITAGIEGPWTQSPTEWDMGYINNLLD
YEWEPEKGPGGAWQWAPKSEELKNSVPDAHDPDEKQTPMMLTTDIALKRD
PDYREVMETFQENPMEFGMNFAKAWYKLTHRDMGPPERFLGPEVPDEEMI
WQDPLPDADYDLIGDEEIAELKEEILDSDLSVSQLVKTAWASASTYRDSD
KRGGANGARLRLEPQKNWEVNEPEQLETVLGTLENIQTEFNDSRSDGTQV
SLADLIVLGGNAAVEQAAANAGYDVEIPFEPGRVDAGPEHTDAPSFDALK
PKVDGVRNYIQDDITRPAEEVLVDNADLLNLTASELTALIGGMRSIGANY
QDTDLGVFTDEPETLTNDFFVNLLDMGTEWEPAADSEHRYKGLDRDTGEV
KWEATRIDLIFGSNDRLRAISEVYGSADAEKKLVHDFVDTWSKVMKLDRF
DLE
3D structure
PDB3vll Crystal Structure and Kinetics Studies on Ser305Ala variant of KatG from HALOARCULA MARISMORTUI and its Complexes with Inhibitor SHA
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R92 H96 H259 W311 D372
Catalytic site (residue number reindexed from 1) R75 H79 H242 W283 D344
Enzyme Commision number 1.11.1.21: catalase peroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A P88 I91 W95 F241 L254 G258 H259 G262 K263 V264 H265 W311 L369 T371 W403 P71 I74 W78 F224 L237 G241 H242 G245 K246 V247 H248 W283 L341 T343 W375
BS02 SHA A H96 D125 P221 H79 D108 P204
Gene Ontology
Molecular Function
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042744 hydrogen peroxide catabolic process
GO:0070301 cellular response to hydrogen peroxide
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vll, PDBe:3vll, PDBj:3vll
PDBsum3vll
PubMed
UniProtO59651|KATG2_HALMA Catalase-peroxidase 2 (Gene Name=katG2)

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