Structure of PDB 3viu Chain A

Receptor sequence
>3viuA (length=703) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEALAKEIGIPEGEYREIVQRLGREPNRVELLLFKVMWSEHCAYKNSRPL
LKALPKEGEAVLQGPGENAGVVRVGEGWAVAFKIESHNHPSAVEPFQGAA
TGVGGILRDIMSMGARPIALLDSLRFGPPEEARSRYLLKGVVSGIAFYGN
AIGVPTVGGDLYFHEGYRENPLVNAMCLGLLREEHLKRSRASLGRPIYYA
GAKTGRDGIVGDPFLGKLLMEATLEAIELDLVEGVQDMGAAGLTSSLSEL
AHKSGLGVELHLDLVPTREEGMTPEELLLSESQERMVLVPKEGKEKALEE
VFGRWGLDCVPVARTIPERVFRVLFRGEVVAEVPTEALAEAPTYVRVGRE
DPEVRRLRETPIPPLEADPQEVLRRLLASPNLASREAVYERYDHQVGTRT
ALLPGKGDAAVLWIKGTRLGVAAKVDQNPRYSRLHPRLGAMHALAEACRN
VSVVGAKPLAYTDGLNLGSPETPEGYHELAETIAGLKEASEALGVPVVSG
NVSLYNESGGKRIPPTAMVGVVGVLEVDKRAEMGFRRPGEVLLLIGEERG
ELGASEVLYLLTGKEFGHPPRLDLGREKAVQEAIRDLIQRGLTRTAHDVA
EGGLLLALAEMTFPYGVGATVEVREEGLEALFGEAPSRVLFTVEKTRLQE
ATLLLEERGLPYRVLGETGGKSLTVLTPGGVLEWSLEELLSAWKAPLREV
LDG
3D structure
PDB3viu Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.5.3: phosphoribosylformylglycinamidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A Y44 E67 K83 E85 D109 D485 S521 G522 N523 V524 Y44 E67 K83 E85 D109 D463 S499 G500 N501 V502
BS02 MG A D430 N472 D620 D408 N450 D598
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004642 phosphoribosylformylglycinamidine synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:3viu, PDBe:3viu, PDBj:3viu
PDBsum3viu
PubMed22232163
UniProtQ5SMH8|PURL_THET8 Phosphoribosylformylglycinamidine synthase subunit PurL (Gene Name=purL)

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