Structure of PDB 3vh2 Chain A

Receptor sequence
>3vh2A (length=582) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SERVLSYAPAFKSFLDTSFFQELSRLKLDTCQPLTVNLDLHNIPKSADQV
PLFLTNRSFEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALE
CWEDGIKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPE
PSLKGLFSKCQKWFDVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDT
STMENVPSALTKNFLSVLQYDVPDLIDFKLLIIRQNEGSFALNATFASID
PDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILP
DLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPV
RQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEA
QHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFD
SYLVMRHGQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAV
ELMTSLLQTKYSGSETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACS
PKVIEAFTDLGWEFVKKALEHPLYLEEISGLS
3D structure
PDB3vh2 Structural basis of Atg8 activation by a homodimeric E1, Atg7.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C488 C569 C465 C546
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008641 ubiquitin-like modifier activating enzyme activity
GO:0019778 Atg12 activating enzyme activity
GO:0019779 Atg8 activating enzyme activity
GO:0042802 identical protein binding
Biological Process
GO:0000422 autophagy of mitochondrion
GO:0006914 autophagy
GO:0006995 cellular response to nitrogen starvation
GO:0015031 protein transport
GO:0016236 macroautophagy
GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway
GO:0032446 protein modification by small protein conjugation
GO:0034727 piecemeal microautophagy of the nucleus
GO:0043412 macromolecule modification
GO:0044804 nucleophagy
Cellular Component
GO:0000407 phagophore assembly site
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0016020 membrane
GO:0097632 extrinsic component of phagophore assembly site membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vh2, PDBe:3vh2, PDBj:3vh2
PDBsum3vh2
PubMed22055191
UniProtP38862|ATG7_YEAST Ubiquitin-like modifier-activating enzyme ATG7 (Gene Name=ATG7)

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