Structure of PDB 3vgl Chain A

Receptor sequence
>3vglA (length=312) Species: 455632 (Streptomyces griseus subsp. griseus NBRC 13350) [Search protein sequence]
GLTIGVDIGGTKIAAGVVDEEGRILSTFKVATPPTAEGIVDAICAAVAGA
SEGHDVEAVGIGAAGYVDDKRATVLFAPNIDWRHEPLKDKVEQRVGLPVV
VENDANAAAWGEYRFGAGQGHDDVICITLGTGLGGGIIIGNKLRRGRFGV
AAEFGHIRVVPDGLLCGCGSQGCWEQYASGRALVRYAKQRANATPENAAV
LLGLGDGSVDGIEGKHISEAARQGDPVAVDSFRELARWAGAGLADLASLF
DPSAFIVGGGVSDEGELVLDPIRKSFRRWLIGGEWRPHAQVLAAQLGGKA
GLVGAADLARQG
3D structure
PDB3vgl Substrate recognition mechanism and substrate-dependent conformational changes of an ROK family glucokinase from Streptomyces griseus
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.2: glucokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H157 C167 C169 C174 H156 C166 C168 C173
BS02 BGC A G66 P79 N104 D105 L134 G135 E154 H157 E176 G65 P78 N103 D104 L133 G134 E153 H156 E175
BS03 ANP A G10 T12 K13 G131 T132 G181 G215 S219 G261 V262 E265 G9 T11 K12 G130 T131 G180 G214 S218 G260 V261 E264
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004340 glucokinase activity
GO:0016301 kinase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
GO:0016310 phosphorylation
GO:0051156 glucose 6-phosphate metabolic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:3vgl, PDBe:3vgl, PDBj:3vgl
PDBsum3vgl
PubMed22101842
UniProtB1VZT1

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