Structure of PDB 3va3 Chain A

Receptor sequence
>3va3A (length=205) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
QLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPD
TTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSGYEALHEIFKVVRK
GIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALA
GLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLG
GWPLS
3D structure
PDB3va3 How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
ChainA
Resolution2.714 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A E25 T26 F29 F77 H120 N121 F124 L164 E20 T21 F24 F72 H115 N116 F119 L159
BS02 dna A R15 H144 F146 R10 H139 F141
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006396 RNA processing
GO:0006974 DNA damage response
GO:0008033 tRNA processing
GO:0031125 rRNA 3'-end processing
GO:0034644 cellular response to UV
GO:0042780 tRNA 3'-end processing
GO:0043628 regulatory ncRNA 3'-end processing
GO:0045004 DNA replication proofreading
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:3va3, PDBe:3va3, PDBj:3va3
PDBsum3va3
PubMed22718982
UniProtP30014|RNT_ECOLI Ribonuclease T (Gene Name=rnt)

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