Structure of PDB 3v9c Chain A

Receptor sequence

>3v9cA (length=499) Species: 5327 (Trametes hirsuta)

AVGPVADLTITDAAVSPDGFSRQAVVVNGVTPGPLVAGNIGDRFQLNVID
NLTNHTMLKSTSIHWHGFFQHGTNWADGPAFINQCPISPGHSFLYDFQVP
DQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHASRYDVDNDDTVITLAD
WYHTAAKLGPRFPGGADATLINGKGRAPSDSVAELSVIKVTKGKRYRFRL
VSLSCNPNHTFSIDGHNLTIIEVDSVNSQPLEVDSIQIFAAQRYSFVLDA
NQAVDNYWIRANPNFGNVGFDGGINSAILRYDGAPAVEPTTNQTTSVKPL
NEVDLHPLVSTPVPGSPSSGGVDKAINMAFNFNGSNFFINGASFVPPTVP
VLLQILSGAQTAQDLLPSGSVYVLPSNASIEISFPATAAAPGAPHPFHLH
GHTFAVVRSAGSTVYNYDNPIFRDVVSTGTPAAGDNVTIRFDTNNPGPWF
LHCHIDFHLEGGFAVVMAEDTPDVKAVNPVPQAWSDLCPTYDALDPNDQ

3D structure

• PDB: 3v9c Crystal structure of T2-depleted fungal laccase from Trametes hirsuta 072 at low and high dose of ionization radiation
• Chain: A
• Resolution: 2.0 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H64 H66 H109 H111 H395 H398 H400 H452 C453 H454 I455 H458 F463
• Catalytic site (residue number reindexed from 1): H64 H66 H109 H111 H395 H398 H400 H452 C453 H454 I455 H458 F463
• Enzyme Commision number: 1.10.3.2: laccase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	A	S21 Q23	S21 Q23
BS02	CU	A	H111 H400 H452	H111 H400 H452
BS03	OXY	A	H109 H111 H398 H452 H454	H109 H111 H398 H452 H454
BS04	CU	A	H66 H109 H454	H66 H109 H454
BS05	CU	A	H395 C453 H458	H395 C453 H458
BS06	CU	A	H64 H66 H398 H400	H64 H66 H398 H400

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0052716 hydroquinone:oxygen oxidoreductase activity

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3v9c, PDBe:3v9c, PDBj:3v9c
• PDBsum: 3v9c
• UniProt: B2L9C1