Structure of PDB 3v8x Chain A

Receptor sequence
>3v8xA (length=853) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence]
EVTGLGKLVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRG
MDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEI
SKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGL
TQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDSS
NYAYFIVKEECKNGSYETCKANPKKDVVGKDERQTVSTRDYTGPNRFLAD
PLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAV
FDANKKQAGSLPGNGKYAGNHKYGGLFTNGENGALVGAEYGTGVFYDETH
TKSRYGLEYVYTNADKDTWADYARLSYDRQGVGLDNHFQQTHCSADGSDK
YCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDKIRHNLSVNLGFDR
FGSNLRHQDYYYQHANRAYSSNTPPQNNGKKISPNGSETSPYWVTIGRGN
VVTGQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYD
YRSTHSDDGSVSTGTHRTLSWNAGIVLKPTDWLDLTYRTSTGFRLPSFAE
MYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIV
RGYEAQIKDGKEEAKGDPAYLNAQSARITGINILGKIDWNGVWYSTFAYN
RVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPEGKWGVNGMLTY
SKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTVKKHFTL
RAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLE
YKF
3D structure
PDB3v8x Structural basis for iron piracy by pathogenic Neisseria.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A R522 Y524 R467 Y469
BS02 SIA A V240 Q241 S242 N298 F300 V187 Q188 S189 N245 F247
BS03 C8E A R432 G434 G474 E475 S476 R478 R379 G381 G421 E422 S423 R425
BS04 C8E A K836 A839 R840 R841 R843 R873 K774 A777 R778 R779 R781 R811
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015091 ferric iron transmembrane transporter activity
GO:0015344 siderophore uptake transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006826 iron ion transport
GO:0033214 siderophore-dependent iron import into cell
GO:0044718 siderophore transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0009279 cell outer membrane
GO:0019867 outer membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v8x, PDBe:3v8x, PDBj:3v8x
PDBsum3v8x
PubMed22327295
UniProtQ9K0U9|TBPA_NEIMB Transferrin-binding protein A (Gene Name=tbp1)

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