Structure of PDB 3v7w Chain A

Receptor sequence
>3v7wA (length=260) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
MKYMITSKGDEKSDLLRLNMIAGFGEYDMEYDDVEPEIVISIGGDGTFLS
AFHQYEERLDEIAFIGIHTGHLGFYADWRPAEADKLVKLLAKGEYQKVSY
PLLKTTVKYKEATYLALNESTVKSSGGPFVVDVVINDIHFERFRGDGLCM
STPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIGSPLVFPKH
HVVSLQPVNDKDFQISVDHLSILHRDVQEIRYEVSAKKIHFARFRSFPFW
RRVHDSFIED
3D structure
PDB3v7w Screening and In Situ Synthesis Using Crystals of a NAD Kinase Lead to a Potent Antistaphylococcal Compound.
ChainA
Resolution2.0102 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.23: NAD(+) kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZAS A D45 L72 F74 Y75 N122 T161 A162 D45 L72 F74 Y75 N118 T157 A158
BS02 ZAS A G46 N122 E123 Y163 S166 G46 N118 E119 Y159 S162
Gene Ontology
Molecular Function
GO:0003951 NAD+ kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
GO:0051287 NAD binding
Biological Process
GO:0006741 NADP biosynthetic process
GO:0016310 phosphorylation
GO:0019674 NAD metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3v7w, PDBe:3v7w, PDBj:3v7w
PDBsum3v7w
PubMed22608967
UniProtQ8Y8D7|NADK1_LISMO NAD kinase 1 (Gene Name=nadK1)

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