Structure of PDB 3v7c Chain A

Receptor sequence

>3v7cA (length=322) Species: 553596 (Staphylococcus aureus A9781)

SKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLKLEGCKID
SVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKS
LVGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSVVLRPNVAFSMIS
KFNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANNDG
IEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQE
IEKRYNQFLTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDYD
GYLIVRDEAGESHRLISADIDF

3D structure

• PDB: 3v7c Selective inhibition of biotin protein ligase from Staphylococcus aureus.
• Chain: A
• Resolution: 2.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	C77	A	S93 T94 Q116 G119 R120 G121 R122 R125 W127 S128 M137 K187 G190 F191 G208 I209 G210 N212 I224 R227	S92 T93 Q115 G118 R119 G120 R121 R124 W126 S127 M136 K186 G189 F190 G207 I208 G209 N211 I223 R226	PDBbind-CN: -logKd/Ki=5.74,Ki=1.83uM

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sun Nov 24 13:07:36 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '3v7c', asym_id = 'A', title = 'Selective inhibition of biotin protein ligase from Staphylococcus aureus.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='3v7c', asym_id='A', title='Selective inhibition of biotin protein ligase from Staphylococcus aureus.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0004077,0006355,0036211', uniprot = '', pdbid = '3v7c', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004077,0006355,0036211', uniprot='', pdbid='3v7c', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>