Structure of PDB 3v5u Chain A

Receptor sequence
>3v5uA (length=297) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence]
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGT
SLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKN
LQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKN
NPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAF
GTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAE
NVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG
3D structure
PDB3v5u Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NA A A47 T50 S51 E213 S236 A47 T50 S51 E206 S229
BS02 CA A T50 S51 E54 T209 S210 E213 T50 S51 E54 T202 S203 E206
BS03 NA A E54 S77 A206 T209 S210 E54 S77 A199 T202 S203
BS04 NA A E54 N81 E213 D240 E54 N81 E206 D233
BS05 CA A I118 D121 G122 D127 I118 D121 G122 D127
Gene Ontology
Molecular Function
GO:0005262 calcium channel activity
GO:0008273 calcium, potassium:sodium antiporter activity
Biological Process
GO:0006874 intracellular calcium ion homeostasis
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v5u, PDBe:3v5u, PDBj:3v5u
PDBsum3v5u
PubMed22323814
UniProtQ57556|Y091_METJA Uncharacterized membrane protein MJ0091 (Gene Name=MJ0091)

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