Structure of PDB 3v4a Chain A

Receptor sequence
>3v4aA (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACTSCSRRFYQLTKLLDSVQPIARELHQ
FTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB3v4a Discovery of diarylhydantoins as new selective androgen receptor modulators.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V716 K720 Q733 M734 I737 Q738 M894 E897 V46 K50 Q63 M64 I67 Q68 M219 E222
BS02 PK1 A L704 L707 G708 M742 M745 V746 F764 M780 H874 T877 I899 L34 L37 G38 M72 M75 V76 F94 M110 H199 T202 I224
External links
PDB RCSB:3v4a, PDBe:3v4a, PDBj:3v4a
PDBsum3v4a
PubMed22897611
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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