Structure of PDB 3v43 Chain A

Receptor sequence
>3v43A (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
HMEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVR
VKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMP
KGMWICQICRPR
3D structure
PDB3v43 Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I260 A275 N277 M278 L279 F280 C281 D282 D285 M300 P301 G303 I59 A74 N76 M77 L78 F79 C80 D81 D84 M99 P100 G102
BS02 ZN A C281 C284 C307 C310 C80 C83 C106 C109
BS03 ZN A C209 C212 H238 C241 C8 C11 H37 C40
BS04 ZN A C230 C233 C259 C262 C29 C32 C58 C61
BS05 ZN A C265 C268 H289 C292 C64 C67 H88 C91
External links
PDB RCSB:3v43, PDBe:3v43, PDBj:3v43
PDBsum3v43
PubMed22713874
UniProtQ92794|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)

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