Structure of PDB 3v1w Chain A

Receptor sequence
>3v1wA (length=349) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
EGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQF
EMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEEDSIYVFKED
EVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGY
FKNKDSEHYKAFKEAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAF
MEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHI
VAFAEEADPDGYEFLEILKSVAQDNTDNPDLSIIWIDPDDFPLLVPYWEK
TFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGE
3D structure
PDB3v1w Molecular Basis for Multiple Ligand Binding of Calsequestrin and Potential Inhibition by Caffeine and Gallocatecin
ChainA
Resolution1.908 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N17 V18 L74 D80 N16 V17 L73 D79
BS02 CA A E199 T229 T277 E198 T228 T276
BS03 CA A D210 P212 N213 E217 D209 P211 N212 E216
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0030955 potassium ion binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0045214 sarcomere organization
GO:0051258 protein polymerization
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:1901341 positive regulation of store-operated calcium channel activity
GO:2001256 regulation of store-operated calcium entry
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0030018 Z disc
GO:0033017 sarcoplasmic reticulum membrane
GO:0033018 sarcoplasmic reticulum lumen

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Cellular Component
External links
PDB RCSB:3v1w, PDBe:3v1w, PDBj:3v1w
PDBsum3v1w
PubMed
UniProtP07221|CASQ1_RABIT Calsequestrin-1 (Gene Name=CASQ1)

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