Structure of PDB 3uwx Chain A

Receptor sequence
>3uwxA (length=945) Species: 550542 (Geobacillus sp. Y412MC52) [Search protein sequence]
MDKIIVKGARAHNLKNIDVEIPRGKLVVLTGLSGSGKSSLAFDTIYAEGQ
RRYVESLSAYARQFLGQMEKPDVDAIEGLSPAISIDQKTTSRNPRSTVGT
VTEIYDYLRLLFARIGRPICPTHGIEIQSQTIEQMVDRLLSYPERTKMQI
LAPIVSGKKGTHAKTLEDIRKQGYVRVRIDREMRELTGDIELEKNKKHSI
DVVVDRIIIKDGIAARLADSLETALKLADGKVVVDVIGEGELLFSEKHAC
PYCGFSIGELEPRLFSFNSPFGACPDCDGLGAKLEVDLDLVIPNDELTLK
EHAIAPWEPYYPQLLEAVCRHYGIPMDVPVKDLPKEQLDKILYGSGGEPI
YFRYTNDFGQVREQYIAFEGVIPNVERRYRETSSDYIREQMEKYMAEQPC
PTCQGYRLKKESLAVLVGGKHIGEVTAMSVTEALAFFDGLELTEKEAQIA
RLILREIRDRLGFLQNVGLDYLTLSRSAGTLSGGEAQRIRLATQIGSRLT
GVLYVLDEPSIGLHQRDNDRLIATLKSMRDLGNTLIVVEHDEDTMLAADY
LIDIGPGAGIHGGEVVAAGTPEEVMNDPNSLTGQYLSGKKFIPIPAERRR
PDGRWLEVVGAREHNLKNVSVKIPLGTFVAVTGVSGSGKSTLVNEVLYKA
LAQKLHRAKAKPGEHRDIRGLEHLDKVIDIDQSPIGRTPRSNPATYTGVF
DDIRDVFASTNEAKVRGYKKGRFSFNVKGGRCEACHGDGIIKIEMHFLPD
VYVPCEVCHGKRYNRETLEVTYKGKNIAEVLDMTVEDALDFFASIPKIKR
KLETLYDVGLGYMKLGQPATTLSGGEAQRVKLAAELHRRSNGRTLYILDE
PTTGLHVDDIARLLDVLHRLVDNGDTVLVIEHNLDVIKTADYIIDLGPEG
GDRGGQIVAVGTPEEVAEVKESHTGRYLKPILERDRARMQARYEA
3D structure
PDB3uwx Structure and mechanism of the UvrA-UvrB DNA damage sensor.
ChainA
Resolution4.398 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C120 H123 C120 H123
BS02 ZN A C274 C277 C404 C407 C274 C277 C400 C403
BS03 ZN A C736 C739 C759 C732 C735 C755
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0009381 excinuclease ABC activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0009432 SOS response
Cellular Component
GO:0005737 cytoplasm
GO:0009380 excinuclease repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3uwx, PDBe:3uwx, PDBj:3uwx
PDBsum3uwx
PubMed22307053
UniProtA0A0E0TG05

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