Structure of PDB 3us3 Chain A

Receptor sequence
>3us3A (length=353) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
EEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQ
FEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEEDSIYVFKE
DEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIG
YFKNKDSEHYKAFKEAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEA
FMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIH
IVAFAEEADPDGYEFLEILKSVAQDNTDNPDLSIIWIDPDDFPLLVPYWE
KTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGE
INT
3D structure
PDB3us3 Glycosylation of skeletal calsequestrin: implications for its function.
ChainA
Resolution1.738 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N17 V18 L74 D80 N17 V18 L74 D80
BS02 CA A E199 T229 T277 E199 T229 T277
BS03 CA A D210 P212 E217 D210 P212 E217
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0030955 potassium ion binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0045214 sarcomere organization
GO:0051258 protein polymerization
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:1901341 positive regulation of store-operated calcium channel activity
GO:2001256 regulation of store-operated calcium entry
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0030018 Z disc
GO:0033017 sarcoplasmic reticulum membrane
GO:0033018 sarcoplasmic reticulum lumen

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Molecular Function
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Cellular Component
External links
PDB RCSB:3us3, PDBe:3us3, PDBj:3us3
PDBsum3us3
PubMed22170046
UniProtP07221|CASQ1_RABIT Calsequestrin-1 (Gene Name=CASQ1)

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