Structure of PDB 3uqb Chain A

Receptor sequence
>3uqbA (length=191) Species: 320372,559292 [Search protein sequence]
PETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDG
IRIQADQTPEDLDMEDNDIIEAHREQIGGSTVVTTESGLKYEDLTEGSGA
EARAGQTVSVHYTGWLTDGQKFGSSKDRNPFAFVLGGGMVIKGWDEGVQG
MKVGGVRRLTIPPQLGYGARGAGGVIPPNATLVFEVELLDV
3D structure
PDB3uqb A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y33 F43 G44 I63 Y89 F106
Catalytic site (residue number reindexed from 1) Y112 F122 G123 I141 Y167 F184
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 A Y33 F53 M61 V62 I63 W66 Y89 F106 Y112 F131 M139 V140 I141 W144 Y167 F184
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006457 protein folding

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3uqb, PDBe:3uqb, PDBj:3uqb
PDBsum3uqb
PubMed24366729
UniProtQ12306|SMT3_YEAST Ubiquitin-like protein SMT3 (Gene Name=SMT3);
Q3JK38

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