Structure of PDB 3uqa Chain A

Receptor sequence
>3uqaA (length=190) Species: 272560,559292 [Search protein sequence]
THINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIR
IQADQTPEDLDMEDNDIIEAHREQIGGSTVVTTESGLKYEDLTEGSGAEA
RAGQTVSVHYTGWLTDGQKFDSSKDRNDPFEFVLGGGMVIKGWDEGVQGM
KVGGVRRLTIPPQLGYGARGAGGVIPPNATLVFEVELLDV
3D structure
PDB3uqa A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
ChainA
Resolution1.55 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y33 F43 D44 I63 Y89 F106
Catalytic site (residue number reindexed from 1) Y110 F120 D121 I140 Y166 F183
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 A Y33 D44 F53 M61 V62 I63 W66 Y89 F106 Y110 D121 F130 M138 V139 I140 W143 Y166 F183
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:3uqa, PDBe:3uqa, PDBj:3uqa
PDBsum3uqa
PubMed24366729
UniProtQ12306|SMT3_YEAST Ubiquitin-like protein SMT3 (Gene Name=SMT3);
Q63J95

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