Structure of PDB 3upr Chain A

Receptor sequence
>3uprA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPW
IEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGC
DVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAR
VAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB3upr Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
ChainA
Resolution1.999 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y59 E63 N66 M67 A69 T73 N77 Y84 Y99 T143 W147 V152 Q155 L156 Y159 W167 Y171 Y6 Y58 E62 N65 M66 A68 T72 N76 Y83 Y98 T142 W146 V151 Q154 L155 Y158 W166 Y170
BS02 1KX A Y9 Y74 V97 Y99 D114 Q115 S116 Y123 I124 W147 Y8 Y73 V96 Y98 D113 Q114 S115 Y122 I123 W146
External links
PDB RCSB:3upr, PDBe:3upr, PDBj:3upr
PDBsum3upr
PubMed22645359
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

[Back to BioLiP]