Structure of PDB 3umk Chain A

Receptor sequence
>3umkA (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
DENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQ
HFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTH
LRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
3D structure
PDB3umk Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A H313 H382 H432 H436 H5 H74 H124 H128
BS02 CU A H327 E368 H19 E60
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3umk, PDBe:3umk, PDBj:3umk
PDBsum3umk
PubMed22245578
UniProtP05067|A4_HUMAN Amyloid-beta precursor protein (Gene Name=APP)

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