Structure of PDB 3um3 Chain A

Receptor sequence
>3um3A (length=377) Species: 9606 (Homo sapiens) [Search protein sequence]
DTHWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDL
SCNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQV
PSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIA
AGIFKHLKESHLPKLITPAEKGRDLESRLIEAYVIQCQAEAQEVTIARAI
ELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYT
AYAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPT
VKPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKIPTEAPQLELKANYGL
VEPIPFEFPPTSVQWTPETLAAFDLTK
3D structure
PDB3um3 Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K141 H144 R145 T195 R198 L202 H204 L208 L350 K141 H144 R145 T195 R198 L202 H204 L208 L350
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007084 mitotic nuclear membrane reassembly
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3um3, PDBe:3um3, PDBj:3um3
PDBsum3um3
PubMed22484091
UniProtQ5VW32|BROX_HUMAN BRO1 domain-containing protein BROX (Gene Name=BROX)

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