Structure of PDB 3ukg Chain A

Receptor sequence

>3ukgA (length=223) Species: 559292 (Saccharomyces cerevisiae S288C)

KASFTDEEDEFILDVVRKNPTRRTTHTLYDEISHYVPNHTGNSIRHRFRV
YLSKRLEYVYEVDKFGKLVRDDDGNLIKTKVLPPSIKRKFSADEDYTLAI
AVKKQFYRDLFQIDPDTGRSPNHVPGSEPNFAAYRTQSRRGPIAREFFKH
FAEEHAAHTENAWRDRFRKFLLAYGIDDYISYYEAEKAQNREPEPMKNLT
NRPKRPGVPTPGNYNSAAKRARN

3D structure

• PDB: 3ukg The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA.
• Chain: A
• Resolution: 2.95 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	K360 A361 S362 F363 H385 H398 T399 N401 S402 H405 R406 Y410 K446 R447 F449 H536 T537 N539 D543 R544 F548 N576 T578 T588 P589 G590 N591 N593 S594	K1 A2 S3 F4 H26 H39 T40 N42 S43 H46 R47 Y51 K87 R88 F90 H158 T159 N161 D165 R166 F170 N198 T200 T210 P211 G212 N213 N215 S216
BS02	dna	A	K360 T383 T384 H385 T386 R404 R408 S444 I445 K446 K448 R518 P520 I521 A522 R523 R542 R546 K547 R580 P589 G590	K1 T24 T25 H26 T27 R45 R49 S85 I86 K87 K89 R140 P142 I143 A144 R145 R164 R168 K169 R202 P211 G212
BS03	CA	A	P503 E506	P125 E128

Gene Ontology

Molecular Function

• GO:0003677 DNA binding

Biological Process

• GO:0000723 telomere maintenance

External links

• PDB: RCSB:3ukg, PDBe:3ukg, PDBj:3ukg
• PDBsum: 3ukg
• PubMed: 22139930
• UniProt: P11938|RAP1_YEAST DNA-binding protein RAP1 (Gene Name=RAP1)