Structure of PDB 3uiw Chain A

Receptor sequence
>3uiwA (length=110) Species: 7955 (Danio rerio) [Search protein sequence]
PGLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVE
LDEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLP
LIEQCRPCCL
3D structure
PDB3uiw A New Mode of Iron-sulfur Cluster Coordination in Glutaredoxins is Crucial for Axonogenesis
ChainA
Resolution2.601 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A K34 C37 Y39 Q69 T80 V81 G93 G94 S95 K26 C29 Y31 Q61 T72 V73 G85 G86 S87
Gene Ontology
Molecular Function
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0001755 neural crest cell migration
GO:0001944 vasculature development
GO:0003147 neural crest cell migration involved in heart formation
GO:0007417 central nervous system development
GO:0008347 glial cell migration
GO:0034599 cellular response to oxidative stress
GO:0060914 heart formation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3uiw, PDBe:3uiw, PDBj:3uiw
PDBsum3uiw
PubMed
UniProtQ6DH06

[Back to BioLiP]