Structure of PDB 3ugx Chain A

Receptor sequence
>3ugxA (length=369) Species: 9913 (Bos taurus) [Search protein sequence]
NHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVY
VSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLI
KKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTD
VEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVS
LSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKT
VAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLAS
STIIKEGIDKTVMGILVSYQIKVKLTVSGLLGELTSSEVATEVPFRLMHP
QPEDDENFVFEEFARQNLK
3D structure
PDB3ugx Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin.
ChainA
Resolution2.649 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PTD A K55 H155 K47 H147
BS02 PTD A Y58 Q87 Y50 Q79
BS03 PTD A Y250 S252 Y242 S244
BS04 PTD A A261 N287 A253 N279
BS05 PTD A K14 F377 K6 F360
BS06 PTD A P127 C128 V130 Q178 S308 S309 T310 I311 P119 C120 V122 Q170 S300 S301 T302 I303
Gene Ontology
Molecular Function
GO:0001664 G protein-coupled receptor binding
Biological Process
GO:0002031 G protein-coupled receptor internalization
GO:0007165 signal transduction
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005829 cytosol
GO:0016020 membrane
GO:0042995 cell projection

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3ugx, PDBe:3ugx, PDBj:3ugx
PDBsum3ugx
PubMed22306737
UniProtP08168|ARRS_BOVIN S-arrestin (Gene Name=SAG)

[Back to BioLiP]