Structure of PDB 3uf0 Chain A

Receptor sequence
>3uf0A (length=249) Species: 471853 (Beutenbergia cavernae DSM 12333) [Search protein sequence]
GPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEI
ADGGGSAEAVVADLADLEGAANVAEELAATRRVDVLVNNAGIIARAPAEE
VSLGRWREVLTVNLDAAWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRN
VAAYAASKHAVVGLTRALASEWAGRGVGVNALAPGYVVTANTAALRADDE
RAAEITARIPAGRWATPEDMVGPAVFLASDAASYVHGQVLAVDGGWLAS
3D structure
PDB3uf0 Crystal structure of a putative NAD(P) dependent gluconate 5-dehydrogenase from Beutenbergia cavernae(EFI target EFI-502044) with bound NADP (low occupancy)
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G20 S143 V153 Y156 K160
Catalytic site (residue number reindexed from 1) G18 S141 V151 Y154 K158
Enzyme Commision number 1.1.1.125: 2-deoxy-D-gluconate 3-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G16 S19 G20 I21 R41 D65 L66 N91 G93 I94 I141 A142 S143 Y156 K160 P186 G187 V189 T191 N193 T194 G14 S17 G18 I19 R39 D63 L64 N89 G91 I92 I139 A140 S141 Y154 K158 P184 G185 V187 T189 N191 T192
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008678 2-deoxy-D-gluconate 3-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

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Molecular Function
External links
PDB RCSB:3uf0, PDBe:3uf0, PDBj:3uf0
PDBsum3uf0
PubMed
UniProtC5BY10

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