Structure of PDB 3uet Chain A

Receptor sequence
>3uetA (length=456) Species: 391904 (Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088) [Search protein sequence]
INLNYLANVRPSSRQLAWQRMEMYAFLHFGMNTMTDREWGLGHEDPALFN
PRNVDVDQWMDALVAGGMAGVILTCKHHDGFCLWPSRLTRHTVASSPWRE
GKGDLVREVSESARRHGLKFGVYLSPWDRTEESYGKGKAYDDFYVGQLTE
LLTQYGPIFSVWLAGANGEGKNGKTQYYDWDRYYNVIRSLQPDAVISVCG
PDVRWAGNAAGHVRDNEWSVVPRRLRSAELTTVSSQDDDLGSREAVAGYG
DNVCWYPAEVDTSIRPGWFYHQSEDDKVMSADQLFDLWLSAVGGNSSLLL
NIPPSPEGLLAEPDVQSLKGLGRRVSEFREALASVRCEARTSSASAAAAH
LVDGNRDTFWRPDADDAAPAITLTLPQPTTINAIVIEEAIEHGQRIEHLR
VTGALPDGTERVLGQAGTVGYRRILRFDDVEVSSVTLHVDGSRLAPMISR
AAAVRI
3D structure
PDB3uet 1,3-1,4-alpha-L-fucosynthase that specifically introduces Lewis a/x antigens into type-1/2 chains
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.111: 1,3-alpha-L-fucosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A G173 V206 W213 E237 D283 G165 V198 W205 E229 D261
BS02 FUC A H36 W47 H85 H86 A174 W290 H28 W39 H77 H78 A166 W268
Gene Ontology
Molecular Function
GO:0004560 alpha-L-fucosidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006004 fucose metabolic process
GO:0016139 glycoside catabolic process
Cellular Component
GO:0005764 lysosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3uet, PDBe:3uet, PDBj:3uet
PDBsum3uet
PubMed22451675
UniProtB7GNN8

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