Structure of PDB 3uer Chain A

Receptor sequence

>3uerA (length=651) Species: 319795 (Deinococcus geothermalis DSM 11300)

GPLGSMLKDVLTSELAAQVRDAFDDDRDAETFLLRLERYGEDLWESLRAV
YGDQVRALPGRLLEVMLHAYHARPAELRRLDEARLLRPDWLQRPEMVGYV
AYTDRFAGTLKGVEERLDYLEGLGVKYLHLMPLLRPREGENDGGYAVQDY
RAVRPDLGTMDDLSALARALRGRGISLVLDLVLNHVAREHAWAQKARAGD
PKYRAYFHLFPDRRGPDAFEATLPEIFPDFAPGNFSWDEEIGEGEGGWVW
TTFNSYQWDLNWANPDVFLEFVDIILYLANRGVEVFRLDAIAFIWKRLGT
DCQNQPEVHHLTRALRAAARIVAPAVAFKAEAIVAPADLIHYLGTRAHHG
KVSDMAYHNSLMVQLWSSLASRNTRLFEEALRAFPPKPTSTTWGLYVRCH
DDIGWAISDEDAARAGLNGAAHRHFLSDFYSGQFPGSFARGLVFQYNPVN
GDRRISGSAASLAGLEAALETGDPGRIEDAVRRLLLLHTVILGFGGVPLL
YMGDELALLNDYAFEDVPEHAPDNRWVHRPQMDWALAERVRQEPSSPAGR
VNTGLRHLLRVRRDTPQLHASIESQVLPSPDSRALLLRRDHPLGGMVQVY
NFSEETVMLPSHVLRDVLGDHVQDRLSGSAFRLDRPTVRLEGYRALWLTA
G

3D structure

• PDB: 3uer Structural Investigation of the Thermostability and Product Specificity of Amylosucrase from the Bacterium Deinococcus geothermalis.
• Chain: A
• Resolution: 2.1 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): D175 D284 E326 H395 D396
• Catalytic site (residue number reindexed from 1): D180 D289 E331 H400 D401
• Enzyme Commision number: 2.4.1.4: amylosucrase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	Z9N	A	F248 A285 F288 E326 D396	F253 A290 F293 E331 D401
BS02	GLC	A	D137 Y140 H180 F248 D284 H395 D396 R520	D142 Y145 H185 F253 D289 H400 D401 R525
BS03	FRU	A	F248 F288 E326 I328 D396	F253 F293 E331 I333 D401
BS04	GLC	A	D137 Y140 H180 F248 D284 H395 D396 R520	D142 Y145 H185 F253 D289 H400 D401 R525

Gene Ontology

Molecular Function

• GO:0047669 amylosucrase activity

Biological Process

• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:3uer, PDBe:3uer, PDBj:3uer
• PDBsum: 3uer
• PubMed: 22210773
• UniProt: Q1J0W0