Structure of PDB 3u92 Chain A

Receptor sequence
>3u92A (length=254) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYE
IRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFS
KPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKIS
TFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCN
LTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRG
SGCP
3D structure
PDB3u92 Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KAI A E13 Y61 P88 T90 R95 G140 A141 T142 E189 E11 Y59 P86 T88 R93 G138 A139 T140 E187 PDBbind-CN: -logKd/Ki=7.48,Ki=32.8nM
BindingDB: Ki=32.8nM
BS02 ZN A E194 K246 E192 K244
BS03 ZN A H93 E96 H91 E94
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3u92, PDBe:3u92, PDBj:3u92
PDBsum3u92
PubMed23141068
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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