Structure of PDB 3u5n Chain A

Receptor sequence
>3u5nA (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCR
DIGKPEVEYDCDAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPN
YYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMM
KVVQKADSEVAQAGKAVALYFEDKLTEIYSDRTFA
3D structure
PDB3u5n A Poised Chromatin Platform for TGF-beta access to master regulators
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D884 N886 E887 D888 W889 N895 G896 G897 D898 L899 C901 E903 S923 G924 D2 N4 E5 D6 W7 N13 G14 G15 D16 L17 C19 E21 S41 G42
BS02 peptide A K1009 H1014 S1015 Q1016 K117 H122 S123 Q124
BS03 ZN A C890 C893 H910 C913 C8 C11 H28 C31
BS04 ZN A C902 C905 C928 C931 C20 C23 C46 C49
External links
PDB RCSB:3u5n, PDBe:3u5n, PDBj:3u5n
PDBsum3u5n
PubMed22196728
UniProtQ9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (Gene Name=TRIM33)

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