Structure of PDB 3tsz Chain A

Receptor sequence
>3tszA (length=341) Species: 9606 (Homo sapiens) [Search protein sequence]
SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRV
NNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFY
IRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVE
RGIIPNKNRAEQLASVQYTKFPAYERVVLREAGFLRPVTIFGPIADVARE
KLAREEPDIYQIAKSEPRDAGTDQRGIIRLHTIKQIIDQDKHALLDVTPN
AVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKL
RKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSE
3D structure
PDB3tsz The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
ChainA
Resolution2.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S432 V433 G434 L435 L437 G439 A448 R480 V484 L487 L488 D514 Y550 N551 G552 L558 R571 S12 V13 G14 L15 L17 G19 A28 R60 V64 L67 L68 D94 Y130 N131 G132 L138 R151
External links
PDB RCSB:3tsz, PDBe:3tsz, PDBj:3tsz
PDBsum3tsz
PubMed22030391
UniProtQ07157|ZO1_HUMAN Tight junction protein ZO-1 (Gene Name=TJP1)

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