Structure of PDB 3tsc Chain A

Receptor sequence
>3tscA (length=271) Species: 1770 (Mycobacterium avium subsp. paratuberculosis) [Search protein sequence]
GKLEGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPSCVPYDPA
SPDDLSETVRLVEAANRRIVAAVVDTRDFDRLRKVVDDGVAALGRLDIIV
ANAGVAAPQAWDDITPEDFRDVMDINVTGTWNTVMAGAPRIIEGGRGGSI
ILISSAAGMKMQPFMIHYTASKHAVTGLARAFAAELGKHSIRVNSVHPGP
VNTPMGSGDMVTAVGQAMETNPQLSHVLTPFLPDWVAEPEDIADTVCWLA
SDESRKVTAAQIPVDQGSTQY
3D structure
PDB3tsc Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
ChainA
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G18 S157 Y170 K174
Catalytic site (residue number reindexed from 1) G16 S155 Y168 K172
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G14 R17 Q19 D38 I39 A52 D77 T78 N104 A105 G106 V107 I155 S157 Y170 K174 P200 P202 V203 T205 M207 G12 R15 Q17 D36 I37 A50 D75 T76 N102 A103 G104 V105 I153 S155 Y168 K172 P198 P200 V201 T203 M205
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

View graph for
Molecular Function
External links
PDB RCSB:3tsc, PDBe:3tsc, PDBj:3tsc
PDBsum3tsc
PubMed28120876
UniProtQ73X99

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