Structure of PDB 3tqu Chain A

Receptor sequence
>3tquA (length=197) Species: 227377 (Coxiella burnetii RSA 493) [Search protein sequence]
MLEIVLASQNSSKLAEMQELLRDLEIKFIPQTEFSVPDIEETGSTFVENA
IIKARHAAKQTGLPALADDSGLTIAALNSAPGVFSSRYAGKNATDAERIQ
KVLEALEAADDSDRSASFHCVIALMENENDPAPLICHGVWEGEIAREPRG
KNGFGYDPIFYVPSHQRTAAELDPQEKNAISHRGQALEQLSTVLTEA
3D structure
PDB3tqu Structural genomics for drug design against the pathogen Coxiella burnetii.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.66: XTP/dITP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E41 D69 E41 D69
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0035870 dITP diphosphatase activity
GO:0036220 ITP diphosphatase activity
GO:0036222 XTP diphosphatase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
Biological Process
GO:0008150 biological_process
GO:0009117 nucleotide metabolic process
GO:0009143 nucleoside triphosphate catabolic process
GO:0009146 purine nucleoside triphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tqu, PDBe:3tqu, PDBj:3tqu
PDBsum3tqu
PubMed26033498
UniProtQ83FA3|IXTPA_COXBU dITP/XTP pyrophosphatase (Gene Name=CBU_0043)

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