Structure of PDB 3tq1 Chain A

Receptor sequence
>3tq1A (length=423) Species: 9606 (Homo sapiens) [Search protein sequence]
MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAV
SYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVM
EIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGL
PQGTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIER
ETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIR
SLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIE
HDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDR
NDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNM
NTSTEWSPPLTMLFLCATKFSAS
3D structure
PDB3tq1 Human DNA Polymerase Eta Is Pre-Aligned for dNTP Binding and Catalysis.
ChainA
Resolution2.556 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q38 Y39 W42 K86 R93 P316 K317 G320 S322 K323 N324 R351 Q38 Y39 W42 K86 R93 P310 K311 G314 S316 K317 N318 R345
BS02 dna A S257 G259 K261 L262 R377 L381 R382 S251 G253 K255 L256 R371 L375 R376
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3tq1, PDBe:3tq1, PDBj:3tq1
PDBsum3tq1
PubMed22154937
UniProtQ9Y253|POLH_HUMAN DNA polymerase eta (Gene Name=POLH)

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