Structure of PDB 3tpy Chain A

Receptor sequence
>3tpyA (length=113) Species: 11855 (Mason-Pfizer monkey virus) [Search protein sequence]
QKQPISKLTRATPGSAGLDLCSTSHTVLTPEMGPQALSTGIYGPLPPNTF
GLILGRSSITMKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVSQGNRIAQ
LILLPLIETDNKV
3D structure
PDB3tpy Crystallization and preliminary X-ray studies of dUTPase from Mason-Pfizer monkey retrovirus.
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A39 R79 S81 K85 D95
Catalytic site (residue number reindexed from 1) A16 R56 S58 K62 D72
Enzyme Commision number 3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUP A G92 V93 I94 D95 Y98 I102 K103 G69 V70 I71 D72 Y75 I79 K80
BS02 UMP A G92 V93 I94 D95 Y98 K103 M105 G69 V70 I71 D72 Y75 K80 M82
External links
PDB RCSB:3tpy, PDBe:3tpy, PDBj:3tpy
PDBsum3tpy
PubMed
UniProtP07570|PRO_MPMV Gag-Pro polyprotein (Gene Name=gag-pro)

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