Structure of PDB 3tp6 Chain A

Receptor sequence
>3tp6A (length=130) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
KLHKEPATLIKAIDGDTVKLMYKGQPMTFRELLVDTPEFNEKYGPEASAF
TKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEAKVRQGLAKV
AYVYKGNNTHEQLLRKAEAQAKKEKLNIWS
3D structure
PDB3tp6 Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E/L103K at cryogenic temperature
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 R35 D40 T41 E43 R87
Catalytic site (residue number reindexed from 1) D16 R30 D35 T36 E38 R76
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D21 D40 T41 E43 D16 D35 T36 E38
BS02 THP A R35 K84 Y85 R87 L89 Y113 Y115 R30 K73 Y74 R76 L78 Y102 Y104
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:3tp6, PDBe:3tp6, PDBj:3tp6
PDBsum3tp6
PubMed
UniProtP00644|NUC_STAAU Thermonuclease (Gene Name=nuc)

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